CONEM Autism Research

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Publications


CONEM collaborates in research and publishes research and review articles in international peer-reviewed journals. The publications are sorted alphabetically by year and title.


Publications 2021


A


Publications 2020


A


Publications 2019


Association Between Catatonia and Levels of Hair and Serum Trace Elements and Minerals in Autism Spectrum Disorder
Tinkov A, Klyushnik T, Simashkova N, Notova S, Kiyaeva E, Skalnaya A, Skalny A, Bjørklund G, Skalnaya M
Biomed Pharmacother 2019;109:174-180. PubMed PMID: 30396074

Determination of Neuroinflammatory Biomarkers in Autistic and Neurotypical Saudi Children
Hamed NO, Al-Ayadhi L, Osman MA, Abdalla O. Elkhawad AO, Bjørklund G, Qasem H, Zayed N, El-Ansary A
Metab Brain Dis 2019;34:1049-1060. PubMed PMID: 31147808

Developmental Toxicity of Arsenic: A Drift from the Classical Dose-Response Relationship
Bjørklund G, Tippairote T, Rahaman MS, Aaseth J
Arch Toxicol. Accepted 13.11.2019

GABA Synaptopathy Promotes the Elevation of Caspases 3 and 9 as Pro-Apoptotic Markers in Egyptian Patients with Autism Spectrum Disorder 
El-Ansary A, Zayed N, Al-Ayadhi L, Qasem H, Anwar M, Meguid NA, Bhat RS, Doşa MD, Chirumbolo S, Bjørklund G
Acta Neurol Belg 2019. doi: 10.1007/s13760-019-01226-z. PubMed PMID: 31673995

ICP-MS Assessment of Hair Essential Trace Elements and Minerals in Russian Preschool and Primary School Children with Attention-Deficit/Hyperactivity Disorder (ADHD)
Tinkov AA, Mazaletskaya AL, Ajsuvakova OP, Bjørklund G, Huang PT, Chernova LN, Skalny AA, Skalny AV
Biol Trace Elem Res 2019. doi: 10.1007/s12011-019-01947-5. PubMed PMID: 31691190

Iron Deficiency, Cognitive Functions, and Neurobehavioral Disorders in Children
Pivina L, Semenova Y, Doşa MD, Dauletyarova M, Bjørklund G
J Mol Neurosci 2019;68:1-10. PubMed PMID: 30778834

Oxidative Stress in Autism Spectrum Disorder
Bjørklund G, Meguid NA, El-Bana MA, Tinkov AA, Saad K, Dadar M, Hemimi M, Skalny AV, Hosnedlová B, Kizek R, Osredkar J, Urbina MA, Fabjan T, El-Houfey A, Kałużna-Czaplińska J, Gątarek P, Chirumbolo S
Accepted Aug 2019 MOLN

The Impact of Auditory Integration Therapy (AIT) on Levels of Plasma Human Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Autism
Al-Ayadhi L, El-Ansary A, Bjørklund G, Chirumbolo S, Mostafa GA
J Mol Neurosci 2019;68:688-695. PubMed PMID: 31073917

The Role of Lipidomics in Autism Spectrum Disorder
El-Ansary A, Chirumbolo S, Bhat RS, Dadar M, Ibrahim EM, Geir Bjørklund
Mol Diagn Ther 2019. doi: 10.1007/s40291-019-00430-0. PubMed PMID: 31691195

The Role of Vitamins in Autism Spectrum Disorder: What do We Know?
Bjørklund G, Waly MI, Al-Farsi Y, Saad K, Dadar M, Rahman MM, Elhoufey A, Chirumbolo S, Jóźwik-Pruska J, Kałużna-Czaplińska J
J Mol Neurosci 2019;67:373-387. PubMed PMID: 30607900

The Role of Zinc Supplementation on the Metallothionein System in Children with Autism Spectrum Disorder
Meguid NA, Bjørklund G, Gebril OH, Doşa MD, Anwar M, Elsaeid A, Chirumbolo S
Acta Neurol Belg 2019. doi: 10.1007/s13760-019-01181-9. PubMed PMID: 31302864

Use of Anti-Histamines and Osthole in Autistic Children
Chirumbolo S, Bjørklund G
Int Immunopharmacol 2019;73:201-202. PubMed PMID: 31103875


Publications 2018


Altered S100 Calcium-Binding Protein B and Matrix Metallopeptidase 9 as Biomarkers of Mesial Temporal Lobe Epilepsy with Hippocampus Sclerosis
Meguid NA, Samir H, Bjørklund G, Anwar M, Hashish A, Koura F, Chirumbolo S, Hashem S, El-Bana MA, Hashem HS
J Mol Neurosci 2018;66:482–491. PubMed PMID:. (IF 2.454)

Cerebral Hypoperfusion in Autism Spectrum Disorder
Bjørklund G, Kern J, Urbina M, Saad K, El-Houfey A, Geier D, Chirumbolo S, Geier M, Mehta J, Aaseth J
Acta Neurobiol Exp (Wars) 2018;78:21-29. PubMed PMID: 29694338 (IF 1.207)

Diagnostic and Severity-Tracking Biomarkers for Autism Spectrum Disorder
Bjørklund G, Meguid NA, El-Ansary A, El-Bana MA, Dadar M, Aaseth J, Hemimi M, Osredkar J, Chirumbolo S
J Mol Neurosci 2018;66:492–511. PubMed PMID:. (IF 2.454)

Impaired Lipid Metabolism Markers to Assess the Risk of Neuroinflammation in Autism Spectrum Disorder
Qasem H, Al-Ayadhi L, Bjørklund G, Chirumbolo S, El-Ansary A
Metab Brain Dis 2018;33:1141-1153. PubMed PMID: 29569150

In the Search for Reliable Biomarkers for the Early Diagnosis of Autism Spectrum Disorder: the Role of Vitamin D
El-Ansary A, Cannell JJ, Bjørklund G, Bhat RS, Al Dbass AM, Alfawaz HA, Chirumbolo S, Al-Ayadhi L
Metab Brain Dis 2018;33:917-931. PubMed PMID: 29497932

Metabolism-Associated Markers and Childhood Autism Rating Scales (CARS) as a Measure of Autism Severity
El-Ansary A, Bjørklund G, Khemakhem AM, Al-Ayadhi L, Chirumbolo S, Bacha AB
J Mol Neurosci 2018;65:265-276. doi: 10.1007/s12031-018-1091-5. PubMed PMID: 29931502

Plasma Concentrations of the Trace Elements Copper, Zinc and Selenium in Brazilian Children with Autism Spectrum Disorder
Saldanha Tschinkel PF, Bjørklund G, Conón LZZ, Chirumbolo S, Nascimento VA
Biomed Pharmacother 2018;106:605-609. doi: 10.1016/j.biopha.2018.06.174. PubMed PMID: 29990849

Probiotic Treatment Reduces the Autistic-Like Excitation/Inhibition Imbalance in Juvenile Hamsters Induced by Orally Administered Propionic Acid and Clindamycin
El-Ansary A, Bacha AB, Bjørklund G, Al-Orf N, Bhat RS, Moubayed N, Abed K
Metab Brain Dis 2018;33:1155-1164. PubMed PMID: 29582256

Relationship between Absolute and Relative Ratios of Glutamate, Glutamine and GABA and Severity of Autism Spectrum Disorder
Al-Otaish H, Al-Ayadhi L, Bjørklund G, Chirumbolo S, Urbina MA, El-Ansary A
Metab Brain Dis 2018;33:843-854. PubMed PMID: 29397522

Selenium and Autism Spectrum Disorder
Skalny AV, Skalnaya MG, Bjørklund G, Gritsenko VA, Aaseth J, Tinkov AA
In: Michalke B (ed) Selenium. Molecular and Integrative Toxicology. Basel: Springer, 2018.  https://doi.org/10.1007/978-3-319-95390-8_10

The Use of Multi-Parametric Biomarker Profiles May Increase the Accuracy of ASD Prediction
Hassan WM, Al-Ayadhi L, Bjørklund G, Alabdali A, Chirumbolo S, El-Ansary A
J Mol Neurosci. 2018;66:85-101. doi: 10.1007/s12031-018-1136-9. PubMed PMID: 30112624

Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder
Bjørklund G, Tinkov AA, Rahman MM, Dadar M, Yassa HA, Aaseth J, Chirumbolo S, Skalnaya MG, Skalny AV
Environ Res 2018;166:234-250. PubMed PMID: 29902778


Publications 2017


Assessment of Gender and Age Effects on Serum and Hair Trace Element Levels in Children with Autism Spectrum Disorder 
Skalny AV, Simashkova NV, Skalnaya AA, Klyushnik TP, Bjørklund G, Skalnaya MG, Tinkov AA
Metab Brain Dis 2017; 32: 1675–1684. PubMed PMID: 28664504

Developmental Neurotoxicants and the Vulnerable Male Brain: A Systematic Review of Suspected Neurotoxicants that Disproportionally Affect Males
Kern JK, Geier DA, Homme KG, King PG, Bjørklund G, Chirumbolo S, Geier MR
Acta Neurobiol Exp (Wars) 2017;77:269-296. PubMed PMID:

Dietary Adequacy of Egyptian Children with Autism Spectrum Disorder Compared to Healthy Developing Children
Meguid NA, Anwar M, Bjørklund G, Hashish A, Chirumbolo S, Hemimi M, Sultan E
Metab Brain Dis 2017;32:607-615. PubMed PMID: 28074329 (IF 2.603)

Hair Toxic and Essential Trace Elements in Children with Autism Spectrum Disorder
Skalny AV, Klyushnik TP, Simashkova NV, Grabeklis AR, Bjørklund G, Skalnaya MG, Nikonorov AA, Tinkov AA
Metab Brain Dis 2017;32:195-202. PubMed PMID: 27581303 (IF 2.603)

Histone Deacetylase Inhibitors, Thimerosal, and Autism Spectrum Disorder
Bjørklund G, Chirumbolo S, Geier DA, Kern JK, Geier MR
Environ Res 2017;156:843–844. PubMed PMID: 28410622 (IF 3.835)

Manganese Exposure and Neurotoxic Effects in Children
Bjørklund G, Chartrand MS, Aaseth J
Environ Res 2017;155:380-384. PubMed PMID: 28282629  (IF 3.835)

May Traffic Air Pollution be Involved in Autism Spectrum Disorder?
Chirumbolo S, Bjørklund G, Urbina MA
Environ Res 2017;154:57-59. PubMed PMID: 28038434 (IF 3.835)

Predictive Value of Selected Biomarkers Related to Metabolism and Oxidative Stress in Children with Autism Spectrum Disorder
El-Ansary A, Bjørklund G, Chirumbolo S, Alnakhli OMMetab Brain Dis 2017;32:1209-1221. PubMed PMID: 28497358 (IF 2.603) 

Relationship between Selenium, Lead, and Mercury in Red Blood Cells of Saudi Autistic Children 
El-Ansary A, Bjørklund G, Tinkov AA, Skalny A, Al Dera HS
Metab Brain Dis. 2017;32:1073-1080. PubMed PMID: 28326463 (IF 2.603)

Tryptophan Status in Autism Spectrum Disorder and the Influence of Supplementation on Its Level
Kałużna-Czaplińska J, Jóźwik-Pruska J, Chirumbolo S, Bjørklund G
Metab Brain Dis 2017;32:1585-1593. PubMed PMID: 28608247 (IF 2.297)


Publications 2016


Acid Glycosaminoglycan (aGAG) Excretion is increased in Children with Autism Spectrum Disorder, and it can be controlled by Diet
Endreffy I, Bjørklund G, Dicső F, Urbina MA, Endreffy EMetab Brain Dis 2016;31:273-278. PubMed PMID: 26464064 – ResearchGate (IF 2.603)

Altered Urinary Porphyrins and Mercury Exposure as Biomarkers for Autism Severity in Egyptian Children with Autism Spectrum Disorder
Khaled EM, Meguid NA, Bjørklund G, Gouda A, Bahary MH, Hashish A, Sallam NM, Chirumbolo S, El-Bana MA
Metab Brain Dis 2016;31:1419-1426. PubMed PMID: 27406246 (IF 2.603)

Evaluation of Whole Blood Zinc and Copper Levels in Children with Autism Spectrum Disorder
Crăciun EC, Bjørklund G, Tinkov AA, Urbina MA, Skalny AV, Rad F, Dronca E
Metab Brain Dis 2016;31:887-890. PubMed PMID: 27059237 (IF 2.603)

Immune Dysfunction and Neuroinflammation in Autism Spectrum Disorder
Bjørklund G, Saad K, Chirumbolo S, Kern JK, Geier DA, Geier MR, Urbina MA
Acta Neurobiol Exp (Wars) 2016;76:257-268. PubMed PMID: 28094817 (IF 1.708)

Mercury as a Possible Link Between Maternal Obesity and Autism Spectrum Disorder
Skalny AV, Skalnaya MG, Bjørklund G, Nikonorov AA, Tinkov AA
Med Hypotheses 2016;91:90-94. PubMed PMID: 27142153 – ResearchGate (IF 1.136)

Nutritional and Environmental Influences on Autism Spectrum Disorder
Bjørklund G, Chartrand M
J Nutr Disorders The 2016;6(1):e123. doi:10.4172/2161-0509.1000e123

The Levels of Blood Mercury and Inflammatory-related Neuropeptides in the Serum are correlated in Children with Autism Spectrum Disorder
Mostafa GA, Bjørklund G, Urbina MA, AL-Ayadhi LY
Metab Brain Dis 2016;31:593-599. PubMed PMID: 26738726 – ResearchGate (IF 2.603)

The Positive Association between Elevated Blood Lead Levels and Brain-specific Autoantibodies in Autistic Children from Low Lead-polluted Areas
Mostafa GA, Bjørklund G, Urbina MA, Al-Ayadhi LY
Metab Brain Dis 2016;31:1047-1054. PMID: 27250967 (IF 2.603)

Vitamin D Status in Autism Spectrum Disorders and the Efficacy of Vitamin D Supplementation in Autistic Children
Saad K, Abdel-rahman AA, Elserogy YM, Al-Atram AA, Cannell JJ, Bjørklund G, Abdel-Reheim MK, Othman HAK, El-Houfey AA, Hashem EA, Abd El-Aziz NHR, Abd El-Baseer KA, Ahmed AE, Ali AM
Nutr Neurosci 2016;19:346-351. PubMed PMID: 25876214 (IF 2.616)


Publications 2015


A Randomized, Placebo-Controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders
Saad K, Eltayeb AA, Mohamad IL, Al-Atram AA, Elserogy Y, Bjørklund G, El-Houfey AA, Nicholson B
Clin Psychopharmacol Neurosci 2015;13:188-193. PubMed PMID: 26243847 – ResearchGate (IF 1.500)

ADHD, Autism and Neuroradiological Complications among Phenylketonuric Children in Upper Egypt
Saad K, Elserogy Y, Abdel Rahman AA, Al-Atram AA, Mohamad IL, ElMelegy TTH, Bjørklund G, El-Houfy AA
Acta Neurol Belg. 2015;115:657-663. PubMed PMID: 25576444 – ResearchGate (IF 1.495)

Levels of Metals in the Blood and Specific Porphyrins in the Urine in Children with Autism Spectrum Disorders
Macedoni-Lukšič M, Gosar D, Bjørklund G, Oražem J, Kodrič J, Lešnik-Musek P, Zupančič M, France-Štiglic A, Sešek-Briški A, Neubauer D, Osredkar J
Biol Trace Elem Res 2015;163:2-10. PubMed PMID: 25234471 – ResearchGate (IF 1.798)

Systematic Assessment of Research on Autism Spectrum Disorder and Mercury Reveals Conflicts of Interest and the Need for Transparency in Autism Research
Kern JK, Geier DA, Deth RC, Sykes LK, Hooker BS, Love JM, Bjørklund G, Chaigneau CG, Haley BE, Geier MR
Sci Eng Ethics 2015. doi:10.1007/s11948-015-9713-6. PubMed PMID: 26507205 (IF 1.454)


Publications 2014


Serum Copper and Zinc Levels in Individuals with Autism Spectrum Disorders
Li SO, Wang JL, Bjørklund G, Zhao WN, Yin CH
Neuroreport 2014;25:1216–1220. PubMed PMID: 25162784 – ResearchGate (IF 1.343)


Publications 2013


The Role of Zinc and Copper in Autism Spectrum Disorders
Bjørklund G
Acta Neurobiol Exp 2013;73:225–236. PubMed PMID: 23823984 (IF 1.708)

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RECENT POSTS

  • Zinc, Copper, and Autism Spectrum Disorder
  • Digestive Enzyme Therapy: A Possible Option in Autism Spectrum Disorder
  • Vitamin D Deficiency Correlates with Severity of Autism and Shows Improvement with Supplementation
  • ADHD, Autism, and Phenylketonuria
  • Serum Zinc and Copper Levels in Autistic Children

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